Researchers at the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (Bei-jing, China; www.cas.cn) have developed a twin-bioengine yeast micro/nanorobot (TBY-robot) with self-propelling and self-adaptive capabilities that can autonomously navigate to inflamed sites for providing gastrointestinal inflammation therapy through enzyme-macrophage switching(EMS).

The TBY-robot was built by asymmetrically immobilizing glucose oxidase and catalase onto the surface of anti-inflammatory nanoparticle-packaged yeast microcapsules.The self-adaptive TBY-robot offers a safe and promising strategy for the precision treatment of gastrointestinal inflammation and other inflammatory diseases.

Image: Twin-bioengine self-adaptive micro/nanorobots developed for gastrointestinal inflammation therapy (Photo courtesy of SIAT)